Guolan New Materials (Shandong) Co., Ltd. is one of the leading manufacturers and suppliers of phosphorus oxychloride 99.5% in China. With a professional production team, we are able to meet the needs of the majority of our customers. Welcome to wholesale bulk top-quality phosphorus oxychloride 99.5% from our factory.
Products Description
The phosphorus oxychloride 99.5% high-purity grade phosphorus oxychloride is a premium formulation engineered specifically for impurity-sensitive fine chemical processes. It delivers POCl₃ content ≥99.50%, PCl₃ impurity ≤0.2%, and boiling-range distillate (105–109°C) ≥97.5%. Beyond meeting the baseline national standard specifications, this grade places particular emphasis on controlling phosphorus trichloride and low-boiling-point impurities, preventing byproduct formation, product discoloration, and yield loss in multi-step synthesis reactions.
Compared to the industrial grade, high-purity phosphorus oxychloride minimizes impurity carry-over at the raw material source, helping pharmaceutical manufacturers and electronic chemical material producers reduce downstream separation and purification costs while improving production consistency for high-value products. Low PCl₃ residue effectively suppresses side reactions, reduces off-spec batches caused by impurities, and enables customers to improve finished product yield while lowering overall production costs.
Guolan New Materials manufactures high-purity grade phosphorus oxychloride under our ISO 9001:2015-certified quality system. Every batch includes additional specialized impurity testing protocols and comes with an extended Certificate of Analysis (COA). We maintain retained sample records for each batch to ensure full traceability, meeting the stringent supplier qualification requirements of pharmaceutical and electronic chemical customers.
Technical Specifications
|
Parameter |
Specification |
|
CAS Number |
10025-87-3 |
|
UN Number |
1810 |
|
Appearance |
Colorless to slightly yellow transparent liquid |
|
POCl₃ Content, wt% |
≥99.50 |
|
PCl₃ Impurity, wt% |
≤0.2 |
|
Distillate Volume (105–109°C), wt% |
≥97.5 |
|
Low-Boiling Component Control |
Proprietary internal control specification |
|
Hazard Classification |
Class 8 (Corrosive) + Class 6.1 (Toxic) |
|
Executive Standard |
HG/T 3606-2009 (high-purity internal control) |
Key Strengths
- Dedicated Low-Impurity Control - Tight control of PCl₃ and low-boiling-point components minimizes byproduct generation in multi-step syntheses, preventing discoloration and yield degradation. This grade is specifically designed for pharmaceutical and electronic chemical processes where raw material impurity tolerance is extremely low.
- Specialized High-Purity QC Protocol - Each batch undergoes additional impurity-specific testing and is accompanied by an extended COA report, satisfying the incoming inspection requirements of pharmaceutical and electronic-grade customers.
- Optimized for High-Value Processes - Formulated for premium applications including pharmaceutical intermediate synthesis, electronic chemicals, and optical glass materials. By reducing purification requirements at the raw material source, it lowers downstream separation costs and ensures consistent quality for high-value end products.
- Full Batch Traceability - Retained samples are kept for every batch to ensure complete traceability. This supports supplier audit requirements for overseas customers.
- Stable Bulk Availability - Leveraging our 100,000-ton annual capacity, the high-purity grade is available in consistent bulk supply to support continuous production at pharmaceutical and electronic material plants. Long-term framework contracts are welcomed.
Key Applications
Pharmaceutical Intermediate Synthesis
High-purity grade phosphorus oxychloride is used in chlorination and cyclization reactions for impurity-sensitive pharmaceutical intermediates. Low PCl₃ content effectively minimizes side reactions, improves target product yield, reduces downstream purification costs, and helps pharmaceutical manufacturers raise finished product pass rates.
Electronic and Optical Chemicals
Electronic-grade chemicals and optical glass material manufacturing impose extremely stringent requirements on raw material impurity levels. Our high-purity phosphorus oxychloride meets electronic-grade synthesis process requirements, minimizing the impact of metal ions and organic impurities on end-product performance.
Premium Agrochemical Intermediates
Used in high-end technical pesticide and export-grade agrochemical intermediate synthesis, helping customers meet the strict purity and impurity specifications of overseas markets and enhance international competitiveness.
R&D and Laboratory Applications
Ideal for synthetic experiments and pilot-scale trials at universities, research institutes, and corporate R&D centers. Reagent purity is stable and reliable, ensuring reproducible experimental results and data accuracy.
FAQ
Q: What additional quality documentation do you provide for high-purity grade?
A: Every high-purity batch includes an extended Certificate of Analysis covering PCl₃, low-boiling components, color, and additional impurity parameters beyond the standard industrial grade. Retained samples are archived for every batch, supporting full traceability and supplier audit requirements for pharmaceutical and electronic chemical customers.
Q: Can you support pharmaceutical or electronic chemical supplier audits?
A: Yes. We have experience supporting GMP-aligned supplier qualification audits and electronic chemical incoming inspection protocols. We can provide batch traceability records, retained sample access, and on-site audit arrangements. Our quality system is ISO 9001:2015 certified with dedicated impurity-testing protocols for high-purity grades.
Q: Is the high-purity grade available in bulk for continuous production?
A: Yes. While the high-purity grade is produced under stricter process control, our 100,000-ton integrated capacity ensures consistent bulk availability. Long-term supply agreements are welcome, with scheduled deliveries aligned to your production planning cycles.
Q: Why is low PCl₃ content critical for pharmaceutical synthesis?
A: Residual PCl₃ acts as a stronger chlorinating agent that can trigger uncontrolled side reactions in multi-step pharmaceutical synthesis, leading to product discoloration, off-spec impurities, and reduced target yield. Our high-purity grade holds PCl₃ ≤0.2% with additional low-boiling-point control, minimizing side reactions and lowering downstream purification burden.
Q: What industries benefit most from the 99.5% high-purity grade?
A: Pharmaceutical intermediate synthesis, electronic-grade chemicals, optical glass materials, and premium export-grade agrochemical manufacturing - any process where raw material impurity tolerance is extremely tight. By controlling impurities at the source, customers reduce downstream separation and distillation costs, improving overall process economics.
Q: How does this grade compare to reagent-grade or electronic-grade POCl₃?
A: Our 99.5% high-purity grade meets or exceeds HG/T 3606-2009 baseline with tightened internal controls on PCl₃ and low-boiling components, making it suitable for most fine chemical and pharmaceutical intermediate applications. For ultra-high purity electronic-grade requirements (sub-ppm metal ions), please contact us - we can discuss custom purification options and analytical reporting scope.
Why Choose Guolan New Materials?
- Dedicated Low-Impurity Process Control - Beyond standard HG/T 3606-2009, our high-purity grade adds internal control on PCl₃ and low-boiling-point impurities. This minimizes side reactions, product discoloration, and yield loss in multi-step synthesis, delivering consistent performance for impurity-sensitive processes.
- Extended COA and Full Batch Traceability - Every high-purity batch ships with an extended impurity analysis report. Retained samples are archived for full traceability. This supports pharmaceutical GMP supplier audits, electronic chemical incoming inspection, and customer quality qualification processes.
- Optimized for High-Value Applications - Engineered for pharmaceutical intermediates, electronic chemicals, optical materials, and premium agrochemicals. By reducing impurity carry-over at the raw material stage, you lower downstream purification costs and improve finished product pass rates.
- Integrated Large-Scale High-Purity Manufacturing - Leveraging our 100,000-ton continuous synthesis platform, we produce high-purity grade at scale without the batch variability typical of small specialty suppliers. Consistent quality from lab-scale R&D through full commercial production.
- Technical Partnership for Fine Chemicals - Our technical team supports customers with process consultation on chlorination and cyclization reactions, impurity impact assessment, and grade selection. We work as a long-term raw material partner for fine chemical manufacturers, not just a commodity supplier.
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